Uriage Presents New Scientific Advances in Triple Barrier Science at EADV Congress 2026 in Vienna

• Clinical and microbiology research showed a correlation between skin barrier repair and microbiome improvement.
• XEMOSE C8+® introduces a new generation of biomimetic ceramides to support skin barrier repair in atopic dermatitis.
• BARIEDERM-CICA+® Repairing Cream supports controlled skin regeneration, with clinically proven anti-mark efficacy from Day 7.
• BARIESUN® ex-vivo research shows that topical non-occlusive polymers can reduce skin penetration of UV filters.

PARIS, Oct. 1, 2026 /PRNewswire/ — Laboratoires Dermatologiques d’Uriage present its latest studies’ results at the 2026 European Academy of Dermatology and Venereology (EADV) Congress.

“The core of modern dermatology lies in a deeper understanding of immune mechanisms of the skin” said Dr Marius Anton Ionescu, MD, PhD, Scientific Communication and Medical Director of Laboratoires Dermatologiques d’Uriage. “At EADV 2026, Uriage shares translational research studies with clinically proven results to support dermatologists’ prescriptions in frequent skin conditions.”

Microbiome Barrier and Clinical Improvement 

The skin microbiome is a key element in chronic inflammatory skin diseases:

• In acne, microbiome imbalance is involved in the inflammatory process. Uriage Repairing Thermal Water (URTW), MPA-REGUL^TM patent and TLR2-REGUL^TM patent, at the heart of the HYSEAC® range, contribute to this microbiome-balancing approach¹.
• In rosacea, the microbiome is also involved in a complex pathophysiology combining physical skin barrier, innate immune receptors, and microbiome changes. Topical care ROSELIANE® improves skin barrier, clinical outcome and skin microbiome².

Atopic Dermatitis: Restoring Skin Barrier And Microbiome with XEMOSE C8+® Biomimetic Ceramides

Atopic dermatitis affects around 20% of children and up to 10% of adults worldwide³.

In atopic dermatitis, the microbiome is part of a complex interaction between skin barrier dysfunction, immune dysregulation, and microbial dysbiosis. Decreased microbial diversity contributes to inflammation and aggravates skin barrier alterations⁴.

Focusing on ceramide deficiency, skin barrier dysfunction and microbiome imbalance, Uriage presents XEMOSE C8+®.  Developed with eight biomimetic ceramides, the C8+ technology is designed to restore both the quantity and diversity of ceramides, helping restore the physical skin barrier while supporting microbiome balance and immune defense⁵. Research and clinical findings show that the XEMOSE C8+® Balm helps soothe itching from the first application, increases ceramide levels within 24 hours and improves physical skin barrier function. Patients with atopic dermatitis having applied XEMOSE C8+® Balm showed improvement of clinical signs of sensitive, dry to very dry, atopy-prone skin atopic dermatitis: -62% Pruritus /-47% Erythema/ -65% Dryness⁶, while increasing skin microbiome diversity⁷.

Skin Regeneration: Advancing Controlled Healing with BARIEDERM-CICA+ ®

The skin healing process can influence the appearance of residual scar marks, which remain a concern for 68% of people living with scars⁸. With BARIEDERM-CICA+® Repairing Cream, Uriage focused on skin regeneration approach by targeting two key elements of healing: maintaining an optimal environment and regulating skin repair. This dual action supports all phases of skin regeneration, while a high-tolerance water-in-oil texture and POLY-2P complex of polymers create a semi-occlusive barrier to maintain controlled hydration, supported by clinically proven anti-mark⁹ from Day 7. BARIEDERM-CICA+® Cream showed -90% redness and damaged skin appearance ⁹.

Photoprotection: BARIESUN® Helps Limit UV Filter Skin Penetration with Non-Occlusive Polymers

In a study on ex vivo human skin, two non-occlusive polymers (Skin Shield Technology^TM in BARIESUN® range) associated with UV filters, showed a decreased skin penetration of UV filters compared to same UV filters formulation without polymers¹⁰.

Uriage Repairing Thermal Water (URTW): The Scientific Foundation Across Uriage Formulations

URTW is the scientific core of every Uriage range. Naturally isotonic and enriched with 11,000 mg/L of minerals and trace elements, it helps optimize skin hydration and reinforce physical, microbiome and immune barriers.

Uriage Pro as a valuable resource for healthcare professionals

Uriage Pro is a platform dedicated to healthcare professionals, providing practical resources and up-to-date dermatology content. Uriage Pro features also one of the largest dermatology atlases with over 12,000 clinical photos available for free download, lifetime collections from Professors Marc Larrègue, Robert Barran and Mourad Mokni¹¹.

Please visit Uriage at Booth 546 (Hall 5, Level 0) at EADV Vienna.

About Laboratoires Dermatologiques d’Uriage 

Laboratoires Dermatologiques d’Uriage is a French dermatological skincare brand that pioneered the Science of the Triple Barrier approach to restore skin health. For over 30 years, the Laboratoires Dermatologiques d’Uriage have partnered with dermatologists to develop advanced dermocosmetics to target skin disorders, from simple irritations to severe conditions. Uriage combines the unique Repairing Thermal Water with dermatological active ingredients to rebalance the microbiome barrier, regenerate the physical barrier, and regulate the immune barrier, with long-lasting effects. Its scientific expertise is backed by 17 patents presented at more than 10 leading international dermatology congresses including the European Academy of Dermatology and Venereology (EADV) Congress.  Available in 80+ countries, Uriage works with a Scientific Advisory Board of +18 dermatologists across 7 countries and 3 continents, including Dr. Marius Anton Ionescu, MD, PhD, Dermatologist, Scientific Communication and Medical Director. The brand also operates a Therapeutic Thermal Center recognized as being of “public interest” by the academy of medicine in 1877, welcoming more than 4,500 patients annually with treatment available from the age of 6 months through adulthood, as part of medically supervised cures.

Media Contact
Elysa Boulard
Global Communication Manager, Laboratoires Dermatologiques d’Uriage (Puig)
elysa.boulard@puig.com

¹ Feuilloley M. Real Therap Dermatol Venereol 2026; 347 (3) : 3-5.
² Ionescu MA. Real Therap Dermatol Venereol 2026; 347 (3) : 8-10.
³ Langan SM, et al. The Lancet. 2020; 396(10247):345–360. 
⁴ Rybojad M. Real Therap Dermatol Venereol 2026; 347 (3) : 5-7.
⁵ Ionescu MA, et al. TeraCILAD Congress 2025; P0640.
⁶ Clinical study performed under dermatological control on 30 subjects all with sensitive skin, dry to very dry skin, prone to atopy. Application twice a day during 30 days of XEMOSE C8+ Balm. Clinical quotation.
⁷ Ionescu MA, et al. Eur Acad Dermatol Venereol Annual Meeting 2026; P0155.
⁸ Tan J, et al. Am J Clin Dermatol. 2022; 23(1):115-123.
⁹Clinical study conducted under dermatological control in 39 subjects following dermo-aesthetic procedures, dermatological surgery, or superficial skin damage. BARIEDERM CICA+ Cream was applied twice daily for 21 days.* Scar thickness improvement observed in a series of 8 patients after dermatological surgery.
¹⁰ Ionescu MA, et al. Eur Acad Dermatol Venereol Annual Meeting 2026; P2430.
¹¹ www.uriagepro.com

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